Mancino became an associate in 2004. Previously, she was a legal intern with the Akron Municipal Court and was an independent consultant assisting the legal department of the Regent Hotel in Las Vegas, Nevada. Mancino was graduated cum laude from Kansas Wesleyan University in 1999 with a double major: criminal justice and psychology. In 2003, she was graduated from the University of Akron School of Law, where she was president of the third-year class and an Outstanding Advocate on the 2003 School of Law Trial Team. Mancino is admitted to practice law in the state of Ohio, United States District Court for the Southern District of Ohio, United States District Court for the Northern District of Ohio, United States District Court for the Sixth Circuit Court of Appeals, Southern District of Illinois and the United States Supreme Court.